A Synthesis of Adaptive Designs in Clinical Trials
A Synthesis of Adaptive Designs in Clinical Trials Publication date: May 2016 / Download PDF Author: Roy Nitulescu, Agnihotram V Ramanakumar, and Vatché Bartekian Abstract Since 2006, when the adaptive design working group presented their work in Washington D.C., the literature on adaptive designs has greatly expanded. Some designs have emerged as inherently better suited to exploratory-phase trials, while others are more appropriate for confirmatory phases of drug development. This article pro...